Dietary Fish Linked to Lower Risk for Type 2 Diabetes in Men

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Dietary Fish Linked to Lower Risk for Type 2 Diabetes in Men

 





Nanri A, Mizoue T, Noda M, et al. Fish intake and type 2 diabetes in Japanese men and women: the Japan Public Health Center-based Prospective Study. Am J Clin Nutr 2011 Jul 20. [Epub ahead of print] 

 

doi: 10.3945/ ajcn.111.012252 

 

http://www.ajcn.org/content/early/2011/07/20/ajcn.111.012252.abstract

http://www.ajcn.org/content/early/2011/07/20/ajcn.111.012252.full.pdf

 

"The current study provides evidence to support a protective role of fish intake against type 2 diabetes in Japanese men," the study authors conclude. "Biological mechanisms underlying the inverse association between fish intake and type 2 diabetes need to be clarified."

 

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Am J Clin Nutr. 2011 Jul 20. [Epub ahead of print]

 

Fish intake and type 2 diabetes in Japanese men and women: the Japan Public Health Center-based Prospective Study.

Nanri A, Mizoue T, Noda M, Takahashi Y, Matsushita Y, Poudel-Tandukar K, Kato M, Oba S, Inoue M, Tsugane S; for the Japan Public Health Center–based Prospective Study Group.

Source

Department of Epidemiology and Prevention, International Clinical Research Center, National Center for Global Health and Medicine, Tokyo, Japan.

 

Abstract

BACKGROUND:

Although fish intake can improve glucose metabolism, results of some prospective studies in Western populations suggest potential adverse effects of environmental contaminants in fish on type 2 diabetes risk. However, data from populations with high fish consumption are scarce.

OBJECTIVE:

We prospectively investigated the association between fish intake and type 2 diabetes risk in Japanese adults.

DESIGN:

The participants were 22,921 men and 29,759 women aged 45-75 y who completed a questionnaire of the second survey for the Japan Public Health Center-based Prospective Study and who had no history of diabetes. Diet was ascertained by using a 147-item food-frequency questionnaire. ORs of self-reported, physician-diagnosed type 2 diabetes over 5 y were estimated by using logistic regression.

RESULTS:

During the 5-y period, 971 new cases (572 men and 399 women) of type 2 diabetes were self-reported. In men, fish intake was significantly associated with a decreased risk of type 2 diabetes; multivariable-adjusted ORs of type 2 diabetes for the highest compared with the lowest quartile of intake were 0.73 (95% CI: 0.54, 1.00; P-trend = 0.04) for total fish and seafood and 0.68 (95% CI: 0.50, 0.92; P-trend = 0.016) for small and medium fish (horse mackerel and sardine, saury and mackerel, and eel). Additional analysis by fat content of fish did not detect any significant association for each category. In women, fish intake was not appreciably associated with type 2 diabetes risk.

CONCLUSION:

In a population with high fish and seafood intake, fish consumption was associated with a lower risk of type 2 diabetes in men but not in women.

 

PMID: 21775559